POS-759 HISTOLOGICAL ANALYSIS OF 3 AND 6 MONTH PROTOCOL BIOPSIES AND OUTCOME SIN ABO INCOMPATIBLE RENAL TRANSPLANTS

Renal transplant is the best renal replacement therapy for patients with ERnd stage disease. ABO incompatible increases chances to undergo but has higher chance on infections and rejections compared compatible transplant. To analyse histological changes at 3 12 month protocol biopsies in transplants (ABOiRTX) correlate them clinical outcomes 1 year. 34 who underwent ABOiKTX between April 2017 March 2018 Muljibhai: Patel Urological Hospital , Nadiad, Gujarat, India were included. Eligible patient a graft biopsy months. The Biopsy samples graded as per Banff correlated 23/34 months [17 6 indication (5 didnot consent, 2 antiplatelets, 4 grafts lost)] 20/23 (2 lost one was antiplatelets)].Protocol revealed no subclinical rejections. 3/17 8/17 had C4d positivity without rejection respectively. Presence of did not significantly influence GFR or Chronicity Analysis 6/23 IFTA, ABMR TCMR Overall TMA over year follow up. At Patient survival 94% death censored 87% (Causes- Graft artery thrombosis, HUS Rejections). Subgroup analysis difference lower doses Rituximab desesnitization (p= 0.6). C4D Tubulo-interstitial inflammation associated reduced increased fibrosis end Lack encouraging. Those normal good